Improvements in Similarity Algorithms Based on Similarity System Theory

VernacularTitle:基于相似系统理论的相似度计算方法的改进
Author: Xueyan ZHAN ; Xinyuan SHI ; Xiaori ZHAN ; Yun WANG ; Yanjiang QIAO
Publication Type:Journal Article
Keywords: Similarity system theory; Similarity algorithms; Process quality control
From: Chinese Journal of Analytical Chemistry 2010;38(2):253-257
CountryChina
Language:Chinese
Abstract: For solving the problem that common similarity algorithms are insensitive to the relative differences of different chromatographic fingerprints data, this paper improved the algorithms of improved extent similarity), which named new improved extent similarity. It was confirmed that new improved extent similarity could distinguish) the samples with the same total difference and different distribution of relative differences. by applying) the similarity algorithm to simulated data and the chromatographic fingerprints of nine batches Rukuaixiao tablets. New improved extent similarity could reflect the relative differences of peak areas more sensitively when the relative differences of common peak areas was less than 100%. The result indicates that new improved extent similarity can reflect the large deviation from the established proportion of components, which can be applied to the control of the fluctuation of the established proportion of effective components and the process quality control of Traditional Chinese Medicine .