The placement of Y-shaped titanium-nickel memory alloy stent in the carina: a fundamental study in experimental canines
- VernacularTitle:实验犬放置镍钛合金气道Y形支架的基础研究
- Author:
Wei BIAN
;
Che SHEN
- Publication Type:Journal Article
- Keywords:
airway obstruction;
carina;
Y-shaped stent;
titanium-nickel memory alloy;
animal experiment;
canine
- From:
Journal of Interventional Radiology
2010;19(2):117-120
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pathological changes of local airway tissue after inserting Y-shaped titanium-nickel memory alloy stent in carina, and to evaluate CT three-dimensional reconstruction technique in postoperative and follow-up observation. Methods Twelve healthy adult canines were enrolled in this study. Based on the information of the carina obtained from CT three-dimensional reconstruction images, the preparation of Y-shape netlike stent was made by knitting method with single Ni-Ti memory alloy wire. The stent was then inserted in canine's carina with the help of a releasing system. After the operation fiberbronchoscopy and CT three-dimensional reconstruction were performed. The animals were sacrificed 12 weeks after the procedure and the bronchus of the stenting segment was removed and sent for histopathologic examination. Results Technical success was achieved in all canines with the stent fight in the carina. The airway remained unobstructed 12 weeks after the procedure. Histopathologic examination revealed that the stent became partial epithelialization. Conclusion The Y-shaped titanium-nickel memory alloy stent has good histecompatibility and physicochemical stability and no re-stenosis of the airway develops in the follow-up period of three months. The stent-releasing technique is easy and simple. As a non-invasive and convenient exam, CT three-dimensional reconstruction technique is of great value in postoperative follow-up observation.
