Progress on breast cancer stem cells as a new target for the studies and treatment of breast cancer
- VernacularTitle:乳腺癌研究及治疗新靶点-乳腺癌干细胞的研究进展
- Author:
Weijun LIU
;
Kunhua WANG
;
Kunmei GONG
;
Yongxue ZHANG
- Publication Type:Journal Article
- Keywords:
breast cancer;
stem cell;
treatment;
target
- From:
China Oncology
2010;20(1):66-69
- CountryChina
- Language:Chinese
-
Abstract:
Since the study of the mechanism of breast cancer occurrence and development deepens, breast cancer stem cells are receiving more and more attention. Studies have shown that a group of breast cancer stem cells were undifferentiated, with self-renewal and multi-differentiation potential. These cells have a resistance to chemotherapy, radiotherapy, hypoxic, high tumorigenic, high invasion and metastasis. In breast cancer's recurrence,development, and even metastasis, they play an extremely important role. In-depth study of breast cancer stem cell related signal transduction pathways and the regulation of microenvironment are meaningful for clinical targeted treatment of breast cancer. Therefore, we summarized the latest development on breast cancer stem cells in the treatment of breast cancer.
