The early diagnostic value of serum Cys-C、β~2-MG、RBP in patients with diabetic nephropathy
- VernacularTitle:血清Cys-C、β_2-MG、RBP在2型糖尿病肾病早期诊断中的价值
- Author:
Yong MA
;
Jibin XU
- Publication Type:Journal Article
- Keywords:
Chalones beta 2-microglobulin;
Diabetic Nephropathies;
Early Diagnosis
- From:
International Journal of Laboratory Medicine
2010;31(2):135-136
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the Cys-C、β~2-MG、RBP as marker三of early diagnosis in patients with diabetic nephropathy Ⅱ(DN).Methods ninety patients with DN were divided into three groups according to urinary albumin excretion rate (UAER),that is normal,micro and mass group.Serum Cys-C、β~2-MG、RBP、BUN,Crea were detected and parallelly contrasted in the three groups and control group with thirty healthy people.Results compared with the control group,the serum Cys-C、β~2-MG、RBP of micro and mass group both significantly increased and the normal group had no significant difference.The positive rate of Cys-C、β~2-MG,RBP in mass group was respectively 100%、100%、96.1%;the positive rate in micro group as follows:Cys C (92.3%)＞B2-MG(84.6%)＞RBP(66.6%)＞Crea(46.1%)＞BUN(28.2%).Conclusion serum Cys-C、β~2-MG、RBP have high positive rates in patients with diabetic nephropathy Ⅱ(DN).They can be used as early diagnostic marker of diabetic nephropathy Ⅱespecially Cys-C.
