Nerve Fibres Distribution in Eutopic Endometrium of Women with Endometriosis
- VernacularTitle:子宫内膜异位症患者在位子宫内膜神经纤维分布的研究
- Author:
Guangling GUO
;
Chunlian ZHANG
;
Lihua FENG
;
Zhentong WEI
;
Li ZHOU
;
Shuangyun CHEN
- Publication Type:Journal Article
- Keywords:
Endometriosis;
Eutopic endometrium;
Nerve fibres
- From:Journal of Practical Obstetrics and Gynecology
2010;26(1):68-70
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Nerve fibres distribution in the functional layer of endometrium of women with endometdosis was investigated.Methods:Histological sections of endometrial tissue were prepared from endometrialcurettings and hysterectomies performed on women with endometnosis(n=25)and without endometriosis(n=40).Immunohistochemistry was used to detect nerve fibres by highly specific polyclonal rabbit antibody PGP 9.5.The assessment of nerve fibre density was performed bv Image Pro Plus Discovery.Results:Nerve fibres were identified throughout the functional layers of the endometrium in all endometriosis patients,but not found in the functional layer of the endometrium in women without endometriosis(P<0.01).Conclusions:Nerve fibres detectad in the functional layer in all women with endometriosis may have important implications for understanding the generation of pain in these patients.
