Application of biological patch in pelvic restoration and reconstruction
10.3969/j.issn.1673-8225.2010.03.036
- VernacularTitle:生物补片在盆底修补和重建中的应用
- Author:
Fan XIAO
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2010;14(3):529-532
- CountryChina
- Language:Chinese
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Abstract:
BACKGROUND: Understanding of patch classification, characteristics, and reaction with host is necessary for best selection of reparative surgery materials.OBJECTIVE: To summarize the patch classification, characteristics and its application in pelvic reconstruction, as well as the complications.METHODS: A computer-based online search of PubMed database (http://www.ncbi.nlm.nih.gov/PubMed) and CNKI database (www.cnki.net/index.htm) was performed for related articles with the key words "patch, polypropylene, compound patch" in Chinese and "reconstructive pelvic surgery, repair, replacement" in English. Articles regarding patch classification, characteristics biocompatibility, and application effect, or in the same circle published recently in authoritative journals were included. A total of 24 articles were finally selected.RESULTS AND CONCLUSION: Polypropylene patch is weaved network, with large mesh, which allows for fiber tissue ingrowth and improves tissue intensity and tensile strength. Leukocyte and macrophage can enter the mesh, so the patch has good anti-infection ability. Expanded polytetrafluoroethylene is soft and smooth, with good tissue tolerance, and can prevent affixion with intraabdominal tissues. Moreover, the submicron pore diameter prevents bacteria invasion. The inflammation and foreign body reaction induced by the expanded polytetrafluoroethylene is the most slight among artificial synthetic materials.
