A Case of Acral Pseudolymphomatous Angiokeratoma of Children (APACHE).
- Author:
Ye Won HAN
1
;
Baik Kee CHO
;
Jun Young LEE
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. jylee@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Acral pseudolymphomatous angiokeratoma of children (APACHE)
- MeSH:
Adult;
Angiokeratoma*;
APACHE;
Arm;
Child*;
Diagnosis;
Endothelial Cells;
Female;
Humans;
Pseudolymphoma;
Vascular Neoplasms
- From:Korean Journal of Dermatology
2007;45(5):477-480
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acral pseudolymphomatous angiokeratoma of children (APACHE) is a recently recognized, rare clinical entity with only 20 reported cases worldwide. It is characterized by unilateral eruptions of multiple angiomatous papules, mostly on acral areas and mainly in children, although some cases have also been reported with involvement of non-acral areas and occurring in adults. The histopathologic examination revealed diffuse dermal infiltrates of lymphohistiocytes and thick-walled vessels lined with prominent plump endothelial cells. APACHE is a cutaneous pseudolymphoma, rather than a vascular neoplasm, because of distinct histopathologic and immunohistochemical findings. We report a case of a 9-year-old girl who presented with multiple angiomatous papules on her right upper arm. The histopathologic and immunohistochemical findings in our patient were consistent with a diagnosis of APACHE.
