Detection of microlymphatic vessels density in oral squamous cell carcinoma
10.3969/j.issn.1001-3733.2010.02.015
- VernacularTitle:口腔鳞癌中微淋巴管密度的检测及其临床意义
- Author:
Yuanqing HUANG
;
Yufeng SONG
;
Jianguo ZHANG
- Publication Type:Journal Article
- Keywords:
Oral squamous cell carcinoma;
Metastasis;
Microlymphatic vessel density;
Lymphangionenesis
- From:
Journal of Practical Stomatology
2010;26(2):202-204
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To approach the role of lymphangiogenesis in oral squamous cell carcinoma(OSCC). Methods: Immunohistochemical double staining technique was utilized to distinguish lymphatic vessels from blood vessels. MLVD was determined by manual counting to analyze the relationship with lymph node metastasis. Results: MLVD was significantly higher in 40 OSCC than 14 normal mucosa(P<0.01). MLVD in OSCC showed a statistically significant relationship with regional lymph node metastasis, depth of invasion(P<0.01). Conclusion: Lymphangiogenesis might occur in growth, infiltration and metastasis of OSCC. Detection of MLVD in OSCC might be important to evaluate tumor metastasis and judge prognosis.
