Detection of antibiotic resistance and disinfectant- resistant gene in Acinetobacter Baumannii

VernacularTitle:鲍曼不动杆菌耐药性分析及耐消毒剂基因的检测
Author: Fang LIU ; Xiaoke HAO ; Xiaofeng HE ; Hu ZHANG
Publication Type:Journal Article
Keywords: Acinetobacter baumannii; Antibiotic resistance; Disinfectant- resistant gene
From: Journal of Practical Stomatology 2010;26(2):157-159
CountryChina
Language:Chinese
Abstract: Objective:To determine the distribution, drug resistance and presence of disinfectant- resistant gene qacE△1- sul1 of Acinetobacter baumannii. Methods: A.baumannii were identified by VITEK- automated microbial identification. Antibiotic susceptive test was carried out by Kirby- bauer (KB). The gene of qacE△1 in A. baumannii was analyzed by polymerase chain reaction (PCR) in 51 multidrug- resistant isolates. Results: 172 strains of the A.baumannii were isolated from January 2008 to November 2009. Susceptible factors were senility, seriousness of underlying disease and invasive operation with infection of A. baumannii. The resistance rate of A. baumannii to Imipenem was 11.1%, but the sensitive rate to the cephlospotins was very low. 49 of 51 strains were qacE△1- sul1 gene positive. Conclusion: The resistance rates to common antibiotic in A.baumannii are high and the resistance patterns are wide. There is high positive percentage of qacE△1- sul1 gene in multidrug- resistant A.baumannii.