Progress in research of Baicalein affecting Alzheimer's disease and improving learning and memory of brain
- VernacularTitle:黄芩素对抗阿尔采末病及改善学习记忆能力的研究进展
- Author:
Yao ZHANG
;
Tianjiao FENG
;
Zhanjun ZHANG
;
Yongyan WANG
- Publication Type:Journal Article
- Keywords:
Alzheimer's disease;
baicalein;
Scutellaria baicalensis C;
Chinese medicine;
learning;
memory
- From:
Chinese Pharmacological Bulletin
2010;26(3):294-297
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease (AD) is a progressive, degenerative disease of the brain, which causes learning and memory to become seriously impaired. AD not only influences the patient's quality of life, but also places a great burden on caregivers. With the increasing of aging population, the pressures can be wide-ranging, involving social, psychological, physical, and economic elements of the caregivers' life.The cause and progression of Alzheimer's disease are not well understood. Currently used treatments include pharmaceutical and psychosocial ones, each offering a small symptomatic benefit. Actually, there are still no available medicines and treatments to delay the progression of the disease. Therefore, the development of a new ideal medicine to treat AD patients becomes the first priority. In recent years, most researchers have turned to natural products, hoping to find a drug candidate to cure AD patient. Baicalein, a traditional Chinese medicine extracted from Scutellaria Baicalensis (Chinese herb), has been demonstrated holding the properties of anti-inflammatory, anti-apoptosis, anti-oxidant, and improving learning and memory of human brain. Baicalein is becoming a potential ideal medicine for treating AD patient.
