The status and prospects of niacin and its combination therapy with statins
- VernacularTitle:烟酸及其与他汀类药物联合治疗现状与展望
- Author:
Chenlu WU
;
Shuiping ZHAO
;
Danhua ZHANG
- Publication Type:Journal Article
- Keywords:
extended-release nicotinic acid;
lipid-regulating effect;
mixed dyslipidemia;
residual cardiovascular risk;
pharmacoeconomics;
combination therapy
- From:
Chinese Pharmacological Bulletin
2010;26(3):414-415
- CountryChina
- Language:Chinese
-
Abstract:
Niacin, a broad-spectrum lipid-regulating agent, can significantly lower plasma triglyceride and raise the high density lipoprotein-cholesterol.Extended-release niacin added to statins monotherapy could further modify the lipid profile and reduce residual cardiovascular risk.This combination therapy provides a safe, effective and economical treatment for clinicians and may be superior to other drugs combined with statins.