New Development of Quantitative Mass Spectrometry-Based Proteomics
10.3724/SP.J.1096.2010.00434
- VernacularTitle:基于质谱技术蛋白质定量方法的研究进展
- Author:
Jinlei ZHU
;
Kai ZHANG
;
Xiwen HE
;
Yukui ZHANG
- Publication Type:Journal Article
- Keywords:
Mass spectrometry;
Proteomics;
Quantitative;
Isotope labeling;
Review
- From:
Chinese Journal of Analytical Chemistry
2010;38(3):434-441
- CountryChina
- Language:Chinese
-
Abstract:
Mass spectrometry has become a powerful technique for proteomics analysis. It would be highly desirable to obtain exact quantitative values of each protein in a system, and these dynamic protein data obtained from cell can provide important information to study protein function, reveal the biological process and discover protein biomarker and drug target. Here, we report the development of quantitative mass spectrometry-based proteomics on strategy, method and application in recent years and further it is addressed for their characteristics and potentialities in protein analysis.
