Experimental Study of Sensitivity in Pulmonary Nodules Detection with Low-dose 64-slice Spiral CT
10.3969/j.issn.1002-1671.2010.01.032
- VernacularTitle:64层螺旋CT低剂量扫描检测肺小结节敏感性的实验研究
- Author:
Yifeng JIANG
;
Jianding YE
;
Xiaoyi DING
;
Qunhui CHEN
;
Yigang YE
- Publication Type:Journal Article
- Keywords:
lung;
pulmonary nodule;
radiation dose;
tomography,X-ray computed
- From:
Journal of Practical Radiology
2010;26(1):115-119
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the sensitivity and optimized scanning parameter of 64-slice spiral CT in detection of pulmonary nodules with different size and density. Methods Three groups of prosthesis nodules with diameter of 2.5～13 mm and different density (soft-tissue, low density, and ground glass opacity,GGO)were taken into the chest phantom equivalent to human tissue,then scanned with Philips Brilliance 64 scanner in standard dose(tube voltage:120 kV, tube current: 250 mAs)and low-dose(tube voltage:120 kV, tube current: 50, 30,and 21mAs) respectively. The radiation dose(CTDIw and DLP) of the scans, Hounsfield unit(HU) and standard deviation(SD) of CT values in different regions of the phantom, and visibility of the nodules was assessed and recorded.Results The radiation dose of 64-slices spiral CT scanning in low-dose(tube current 21～51 mAs) decreased to 8%～20% of which scanning in standard-dose(250 mAs). There was no statistical difference between the CT values in different regions of the phantom (P>0.05), while the SD of CT values was of statistical significantce (P<0.001) and SD increased with the increment of the density under different scanning parameters. None of the nodules besides of GGO nodules with 2.5 mm and 4 mm in size scanned at 21 mAs was invisible. Conclusion GGO nodules of 2.5 mm in diameter can be detected with 64-slice spiral CT using 30 mAs at experimental study, which might be the optimized dose for detecting pulmonary nodules.
