Preparation and characteristics of starch/polyvinyl alcohol compound bio-membrane

VernacularTitle:淀粉/聚乙烯醇复合生物膜的制备及其表征
Author: Aichen ZHU ; Rui SHI ; Dafu CHEN ; Runying YUAN ; Liqun ZHANG
Publication Type:Journal Article
From: Chinese Journal of Tissue Engineering Research 2010;14(8):1414-1417
CountryChina
Language:Chinese
Abstract: BACKGROUND: There is no study on starch/polyvinyl alcohol (PVA) as guided tissue regeneration membranes. The guided tissue regeneration membrane with porous structure were prepared, which combined with the advantages of natural polymer and synthetic polymer. OBJECTIVE: To research the effects of the preparation conditions on the properties of starch/PVA membranes. METHODS: The porous membranes of guiding tissue regeneration were prepared mainly by starch and PVA through solution mixing, casting, freezing and drying. The effects of the mass ratio of PVA and starch, solution concentration, and pre-freezing temperature on the properties of the membrane were researched. The surface morphology, tensile strength, porous ratio, water absorbance and cell cytotoxicity were characterized. RESULTS AND CONCLUSION: The aperture of the membrane was 1-50 μm, the porosity was 60%-70%, and the tensile strength was 12-26 MPa. And this membrane had the excellent biocompatibility and hydrophilicity. The pores in the surface were evenly distributed with the solution concentration of 5% and the pre-freezing temperature of -30℃. The more content of starch was, and the larger of the aperture was.