Effects of oxytocin on hemodynamics during epidural block
- VernacularTitle:催产素对硬膜外阻滞患者血流动力学的影响
- Author:
Jinzhi ZHANG
;
Limin ZHENG
- Publication Type:Journal Article
- Keywords:
Oxytocin;
Epidural block;
Hemodynamics
- From:
The Journal of Clinical Anesthesiology
2010;26(3):212-214
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of oxytocin on hemodynamies in patients under epidural block.Methods Twenty-six selective myomectomy patients were randomly divided into epidural block group(E) and general anesthesia group(G) with 13 cases each.Epidural anesthesia with 2 % lidocaine was performed with the blocking plane of T_6-T_8.Group G was given general anesthesia with propofol,fentanyl,remifentanyl and vecuroniurn.Oxytocin 5 U was injected in 30 s when hysteromyoma was removed and the hemodynamics was stable.MAP and HR were recorded before and after oxytocin injection.Results Compared to those before,MAP was decreased and HR was increased after oxytocin injection in both groups(P<0.05 or P<0.01).The decrease of MAP was slower but lasted for a longer period in group E than those in group G(P<0.05 or P<0.01).Conclusion Epidural blockade may aggravate the hypotensive effect of oxytocin and inhibit oxytocin-induced HR increasise.
