Effects of acute hypervolemic hemodilution with HSH 40 on hemodynamics and fluid balance in patients antler general anesthesia
- VernacularTitle:高渗氯化钠羟乙基淀粉40注射液急性高容量血液稀释对全麻患者液体平衡的影响
- Author:
Xihua LU
;
Yi ZHOU
;
Jianwei WANG
- Publication Type:Journal Article
- Keywords:
Hypertonic sodium chloride hydroxyethyl statch 40;
Acute hypervolemic hemodilution
- From:
The Journal of Clinical Anesthesiology
2010;26(3):215-216
- CountryChina
- Language:Chinese
-
Abstract:
Objective To obeserve the effects of acute hypervolemic hemodilution(AHH) with hypertonic .sodium chloride hydroxyethyl starch 40(HSH 40) on hemodynamics and fluid balance in patients under general anesthesia.Methods Fifty patients undergoing radical surgery for gastral cancer under general anesthesia were randomly divided into 2 groups with 25 patients each.Acute hypervolemic bemodilution (AHH) was performed with HSH 40 6 ml/kg in group A or with hydroxyethyl statch(HES) 6 ml/kg in group,which was infused within 30 minuts.HR,MAP,CVP were recorded before(T_0),at 30 min (T_1),60 min (T_2) after infusionand and the end of operation (T_3).The amounts of bleeding,HSH 40 and HES and urine output were recorded as well.Results There were no significant diferences in HR and MAP between two groups at all time points.CVP was sighificantly higher at T_1-T_3 than that at To in two groups.The urine output was more in groups A than that in group B(P<0.05).Conclusion AHH with HSH 40 can effectively expand blood vlume and increase urine output in surgical patients under general anesthesia.
