Effects of limb ischemia-reperfusion injury on blood coagulation
- VernacularTitle:肢体缺血-再灌注损伤对凝血功能的影响
- Author:
Shiyang DONG
;
Cunming LIU
- Publication Type:Journal Article
- Keywords:
Ischemia-reperfusion injury of the limbs;
Blood coagulation;
Thrombelastography
- From:
The Journal of Clinical Anesthesiology
2010;26(3):224-226
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of limb ischemia-reperfusion injury(I-RI) on blood coagulation.Methods Eighteen patients scheduled for unilateral knee arthroscopy surgery under epidural anesthesia were treated with an inflatable tourniquet to ptoduce ischemia for (42 ± 6) min.Venous blood was taken before tourniquet inflation,at 30 min during ischemia,3 min and 30 min during reperfusion for measuring blood coagulation by thrombelastography(TEG).Results TEG showed the decreases in reaction time(R value) and coagulation time(K value),and the increases in alpha angle(α) and maximal amplitude(MA),which were all within the normal limits and had no significant differences among four time points of testing.Conclusion I-RI of the limbs has no significant effects on blood coagulation.
