Research status and application progression in periodontal locally sustained-release antimicrobials
10.3969/j.issn.1673-8225.2010.08.026
- VernacularTitle:牙周局部缓释型制剂的研究现状及应用进展
- Author:
Dan WANG
;
Jiayin DENG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2010;14(8):1437-1441
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: Local application of sustained-release antimicrobials serve as an adjuvant therapy of periodontitis, and the dosage form, medicine and carrier material have greatly developed. OBJECTIVE: To summarize the currant situation and progression of periodontal local sustained-release antimicrobials at home and abroad.METHODS: A computer-based online search of CNKI and Pubmed (1999-01/2009-10) was performed for the related articles about sustained-ralease antimicrobials, with the key words "periodontitis, treatment, medication, and sustained-ralease". The articles in the same field published recently or in authoritative journals were selected. A total of 143 articles were collected, and 40 related sustained-ralease antimicrobials were included.RESULTS AND CONCLUSION: Application of sustained-release antimicrobials is a well adjuvant therapy for some special clinical periodontitis. It is widely used due to its low dosage, long lasting-time and well target effect. The clinical application of sustained-ralease antimicrobials is promising along with the development of compound medicine and periodontal tissue regeneration.
