Study on the Correlation between the Appearances of DSA and Serum VEGF Expression in Cervical Cancer

VernacularTitle:宫颈癌的DSA表现与血清VEGF表达的相关性研究
Author: Junyi XIANG ; Chenhui QI ; Fangman CHEN
Publication Type:Journal Article
Keywords: cervical cancer; vascular endothelial growth factor; angiography
From: Journal of Practical Radiology 2010;26(4):561-565
CountryChina
Language:Chinese
Abstract: Objective To study the correlation between ths DSA manifestations and expression of serum VEGF in the patients with cervical cancer.Methods Imaging data of 40 cases with cervical cancer confirmed by clinic were collected,and DSA were performed during interventional therapy in all cases,and the serum VEGF was detected by enzyme-linked immunosorbent assay(ELISA)which was compared with that in 40 healthy women as contrast.Results(1)Serum VEGF level in the patients with cervical cancer was significantly higher than that in control group(P＜0.01),and the serum VEGF level was significantly higher in Ⅲ and Ⅳ stage of cervical cancer than that in Ⅱ stage(P＜0.05).(2)There was positive correlation between tumor stain in DSA and the serum level of VEGF(P＜0.05).Conclusion There was positive correlation between the degree of blood supply and the serum level of VEGF.