Relationship between serum amyloid A and Insulin resistance in patients with metabolic syndrome

VernacularTitle:代谢综合征患者血清淀粉样蛋白A水平与胰岛素抵抗的关系
Author: Bicheng HU
Publication Type:Journal Article
Keywords: metabolism syndrome; amyloid protein AA; insulin resistance
From: International Journal of Laboratory Medicine 2010;31(6):573-574
CountryChina
Language:Chinese
Abstract: Objective To probe the relationship between serum amyloid A and insulin resistance in patient with metabolic syndrome.Methods Parameters of body height,body weight,waistline,SBP,DBP,TG,TC,FPG,and HDL were measured in the group of 40 patients with metabolic syndrome while 30 healthy people were referred as control group.Results The level of serum SAA,HOMA,and IR were significantly higher than those of the control group(P<0.01),and the other parameters were also indicated significantly difference(except the parameters of age,height,TC,and LDL-C).In patients of metabolic syndrome,the SSA had a positive correlation with body weight,waistline systolic pressure LDL-C,FINS,HOMA and IR,while the SSA had a negative correlation with HDL-C.Conclusion SAA is closely associated with insulin resistance,and it may serve as a marker in patients with metabolic syndrome