The effect of AD injection on immune functions in tumor-bearing mice
- VernacularTitle:癌迪针剂对荷瘤小鼠免疫功能的影响
- Author:
Jinxia AI
;
Liang LIU
- Publication Type:Journal Article
- Keywords:
AD-injection;
Antitumor;
Immunological function
- From:
Chinese Journal of Immunology
2010;26(3):224-227
- CountryChina
- Language:Chinese
-
Abstract:
Objective:In order to study the antitumor effect of AD injection and its immunological mechanisms.Methods:Liver cancer H22-bearing mice were treated with AD injection and 7 days later to observe the effect of AD injection on the inhibitory rate of tumor,indexes of thymus and spleen,lymphocytes transformation function,phagocytosis of the peritoneal macrophage,activity of TNF,the level of IL-2 and IFN-α in serum.Results:AD injection could inhibit the growth of tumor in bearing mice significantly and promote the transformation function of lymphocytes and enhance the peritoneal macrophage phagocytosis and the activities of TNF.AD injection could improve the level of IL-2 of spleen cells and IFN-α in serum.Conclusion:These results suggested that AD injection could obviously inhibit the growth of tumor and enhance the immune functions in bearing mice.
