TO EVALUATE THE EFFICACY OF LIGUSTRAZIN AND SALVIA MILTIORRHIZA COMBINED PREDNISONE TO TREAT IDIOPATHIC PULMONARY FIBROSIS
- VernacularTitle:中药丹参、川芎联合强的松治疗特发性肺纤维化的临床疗效
- Author:
Jie HOU
;
Lingjuan DAI
;
Guohua MU
- Publication Type:Journal Article
- From:
Chinese Journal of Postgraduates of Medicine
2001;24(1):17-18
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Use ligustrazin and salvia miltiorrhiza to treat idiopathic pulmonary fibrosis,for the experimental result was perfect in animal modal.Method:These two drugs combined with prednisone in 15 patients as treated group,prednisone in 10 patients as control group.Result:At 1,6 months followed up,the dyspnea and cough improved markedly.Chest radiograph and pulmonary function improved slightly.There were no differences between two groups.After 24 month the combined group 13(73%) stabilized,4(27%) relapse or deterioration,no death.Control group 6(60%) stabilized,3(30%) relapse or deterioration,1(10%) death,Conclusion:Combined group was better then control group.Ligustrazin and salvia miltorrhiza could decrease alveolitis and inhibit the formation of procollagen.It also improve the patient's immunity.
