Clinical Significance of Determining TXB2、PAgT、6-Keto-PGF1α in Plasma of Lung Carcinoma Patients
- VernacularTitle:肺癌患者TXB2、PAgT、6-Keto-PGF1α的临床意义
- Author:
Wuming WANG
;
Chunyan GENG
;
Jing XU
- Publication Type:Journal Article
- From:
Journal of Chinese Physician
2001;3(5):335-337
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical significance of determining the levels of plasma TXB2,PAgT,6-Keto-PGF1α in the lung carcinoma patients.Methods The levels of plasma TXB2,PAgT and 6-Keto-PGF1α were determined in 43 patients with lung carcinoma and 45 healthy controls,and 36 cases of 43 patients with lung carcinoma were randomly divided into two groups:(A) conventional treatment plus warfarin sodium,(B) conventional treatment without anticoagulant.We also determined the level of plasma Fib in both group A and group B,besides examined the levels of plasma TXB2,PAgT and 6-Keto-PGF1α before and after treatment.Results Statistical analysis showed that the levels of TXB2 and PAgT were significantly higher,but the levels of 6-Keto-PGF1α was significantly lower in the patients with lung carcinoma than those in healthy controls(P＜0.05～0.01).The levels of TXB2,PAgT and Fib in group A were significantly lower,but the level of 6-Keto-PGF1α was significantly higher in group A after treatment than before treatment(P＜0.05～0.01).While these four indexes in group B did not significantly change(P＞0.05).Conclusion The determination of plasma TXB2,PAgT and 6-Keto-PGF1α for lung carcinoma patients are helpful in diagnosis and treatment of lung carcinoma.
