Investigation on the changing spectrum and antibiotic resistance of the pathogenic bacteria in general surgical infections
- VernacularTitle:普通外科感染的菌种变迁及耐药性检测
- Author:
Li REN
;
Chengji CAI
;
Bijie HU
- Publication Type:Journal Article
- From:
Chinese Journal of General Surgery
2001;16(5):286-288
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changing spectrum and antibiotic resistance of the pathogenic bacteria isolated from general surgical infections. Methods The relevant bacterial materials from 557 patients with general surgical infection from June 1993 to July 1997 were investigated. Results 1 045 strains in 38 species of gram-negative bacteria and 418 strains (8 species) of gram-positive bacteria were isolated with a negative over positive rate of 71.4% to 28.6%. For gram-negatives, E coli was the most common, and enterobactor cloacae ranking the third was on a dramatic increase from isolations. Staphylococcus aureus and staphylococcus epidemidis were the most common gram-positive species followed by enterococcus faecalis. Enterobactor cloacae and enterococcus faecalis are multi-antibiotic resistant bacteria. The result of drug susceptibility test showed that gram-negative bacteria were sensitive to fluoroqinolones or third-generation cephalosporins while gram-positive bacteria were sensitive to vancomycin and rifampicin. Conclusion This study showed that the rational application of antibiotics is very important to suppress the spectrum changing and antibiotic resistance of the bacteria.
