The experimental study on canine acute myocardial infarction with intravenous real-time myocardial contrast enhancement imaging
- VernacularTitle:经静脉实时心肌声学造影评价犬急性心肌梗死的实验研究
- Author:
Zenghui HAN
;
Yunqiu QIAN
;
Haili SU
- Publication Type:Journal Article
- From:
Chinese Journal of Ultrasonography
2001;10(5):304-306
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the value of real-time myocardial contrast enhancement imaging (real-time MCE) on acute myocardial infarction.Methods Eight open-chest canine models of myocardial infarction were established by ligating left anterior descent branch of coronary artery (LAD) on level after first diagonal branch. The real-time MCE, using intravenous instillation of a new kind of Perfluorocarbon contrast agent， were performed before the occlusion, 1 hour and 3 hours after the occlusion. The myocardial contrast agents perfusion and wall motion was observed on the middle of papillary muscles scan plane.Results The real-time MCE showed not only the black aridity of contrast agents but also the wall motion abnormality 1 hour and 3 hours after the occlusion. In comparison with pathology, the defects of contrast perfusion were larger than the stained infarction zones. In addition, the flash contrast imaging revealed the reperfusion defect of adjacent zones.Conclusions With the ability of showing the myocardial microcirculation and wall motion function simultaneously, the real-time MCE makes MCE exam significantly easier to perform. Finally, flash contrast imaging will be the cornerstone upon which perfusion quantification will be built.
