Research on Realgar Inducing Apoptosis of Leukemia
- VernacularTitle:中药雄黄诱导白血病细胞凋亡的研究
- Author:
Hao ZHAO
;
Weiguo LI
;
Lei ZHAO
- Publication Type:Journal Article
- Keywords:
Realgar;
Apoptosis
- From:
International Journal of Traditional Chinese Medicine
2008;30(2):92-93
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the influence of realgar on apoptosis and Bcl-2 expression of leukemia.Methods Realgar treatment group and adriamycin(ADR)treatment group were established,and the indexes involved with OD value of cell strain,morphologic alteration of apoptosis,and positive expressive rate of Bcl-2 were observed in the two groups.Results Compared with ADR treatment group,OD value and Bcl-s positive expressive rate were significantly decreased(P＜0.05)and apoptotic rate was significantly increased in realgar group(P＜0.05).Conclusion Realgar has excellent effect to induce apoptosis of leukemia.
