Artemisinins regulate apoptosis genes of neoplasm
- VernacularTitle:青蒿素对肿瘤细胞凋亡相关基因的调控
- Author:
Qingchun LI
;
Ziguo LUO
- Publication Type:Journal Article
- Keywords:
Artemisinin;
Tumor;
Apoptosis;
Genet
- From:
International Journal of Traditional Chinese Medicine
2008;30(2):119-121
- CountryChina
- Language:Chinese
-
Abstract:
Artemisinin and its derivatives,which are known as traditional antimalarial drugs,have anticancer activities by inhibiting cell proliferation,inducing apoptosis of tumor cells,and resisting angiogenesis,etc.The activity of inducing apoptosis has become high-light for studies recently.Most scholars believed this activity was obtained by increasing apoptosis-inducing genes(Bax),decreasing anti-apoptosis genes(Survivin,Bcl-2),and regulating two-ways controlling genes,and finally led to the distinctive morphological changes.
