The Effects of Modifded DaHuang ZheChong Pill on T Lymphocyte Subpopulation in Tumor-bearing Mice
- VernacularTitle:大黄(庶虫)虫丸加减方对荷瘤小鼠T淋巴细胞亚群的影响
- Author:
Hua AI
;
Bo JIANG
- Publication Type:Journal Article
- Keywords:
DaHuangZheChong Pill;
Tumor-bearing mice;
T lymphocyte subpopulation
- From:
International Journal of Traditional Chinese Medicine
2008;30(2):90-91
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of Modifded DaHuang ZheChong Pill on T lymphocyte subpopulation of S180 tumor-bearing mice.Methods The mice were built to the S180 sarcoma model.The experimental animals were divided into 5 groups:High-dose Modifded DaHuang ZheChong Pill group.middle-dose Modifded DaHuang ZheChong Pill group,low-dose Modifded DaHuang ZheChong Pill group,model group,and normal group.The proportion of the T lymphocyte subpopulation was detected by Flow Cytometer in the different experimental groups.Results Modifded DaHuang ZheChong pill could control radio of CD4/CD8,especially,in the high dosage group.Conclusion Modifded DaHuang ZheChong Pill could remit and improve the immune function in tumor-bearing mice,showing the best results in High-dose Modifded DaHuang ZheChong Pill group.
