Analysis of high risk factors related to early-onset myocardial damage in multiple trauma patients
- VernacularTitle:多发伤早期心肌损害的高危因素分析
- Author:
Weifeng SHEN
;
Xiaoyan SHI
;
Xiaogang ZHANG
;
Guanyu JIANG
;
Yingyu FU
- Publication Type:Journal Article
- Keywords:
Multiple trauma;
Myocardium;
Risk factor
- From:
Chinese Journal of Emergency Medicine
2005;14(4):269-273
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate potential clinical risk factors for the development of early-onset myocardial damage following multiple trauma (MT), and to determine whether early-onset myocardial damage was caused by the combined effects of thoracic and systemic injury factors in MT patients.Methods A total of 231 patients with MT over the last 3 years were retrospectively reviewed. With myocardial damage being a dependent variable and other twenty factors being independent variables, univariate and multivariate logistic regressions were applied to investigate the risk factors for early-onset myocardial damage and to identify the association of thoracic and systemic risk factors with early-onset myocardial damage.Results Multivariable logistic regressions showed that acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ ) score ≥10, injury severity score (ISS) ≥ 25, shock index ≥ 2,coexisting chest trauma, abbreviated injury scale (AIS) of chest≥3, and hypoxia time ≥ 0.5 h were risk factors. The risk of earlyonset myocardial damage following MT obviously increased when thoracic and systemic injury risk factors were coexisting.Conclusion Our results indicated that thoracic injury combined with systemic injury increased the overall risk of early-onset myocardial damage following MT. Prospective validation of these findings in other clinical settings is warranted.
