Clinical Observation on Therapeutic Effects of Treatment of Diabetic Peripheral Neuropathy with Integrative Traditional Chinese and Western Medicine
- VernacularTitle:中西医结合治疗糖尿病周围神经病变的疗效观察
- Author:
Changxiu GUO
;
Nanfang LOU
;
Hua SUN
;
Xu LIAN
- Publication Type:Journal Article
- Keywords:
Diabetic peripheral neuropathy;
Dan-Hong injection;
Methycobal
- From:
International Journal of Traditional Chinese Medicine
2008;30(2):151-152
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of Dan-Hong Injection and Methycobal combined therapy in treating diabetic peripheral neuropathy(DPN).Methods 72 cases of peripheral neuropathy and type 2 diabetes(conformed to ADA standard published in 1999)were randomly separated into an experimem group and a control group.Members in the experiment group were treated with Dan-Hong injection 20ml/day i.v.and Methycobal 500ug/day i.m.Members in the control group were treated with Methycobal only.At the end of 2 weeks'therapeutic courses,motor nerve conducdon velocity (MNCV)and sural nerve conduction velocity(SNCV)were evaluated.Results The overall effective rate was 92.1% in the experiment group and 67.6% in the control group,showing significant difference between the two groups(P<0.01).The post-therapeutic values of both SNCV and MNCV were significantly different from those of previous treatment.(P<0.01)The post-therapeutic values of SNCV and MNCV of the experiment group were also significantly different from those of the control group(P<0.05).No evidently relative adverse effects were observed in both groups.Conclusions Combined therapy of Dan-Hong injection and Methycobal was more effective in controlling the clinical activity of diabetic peripheral neuropathy.