Progress on the parameters of the healing of intestinal anastomoses
- VernacularTitle:肠管吻合愈合参数的研究进展
- Author:
Chunhui PENG
;
Yajun CHEN
- Publication Type:Journal Article
- Keywords:
healing;
intestine;
parameters
- From:
International Journal of Surgery
2008;35(3):199-202
- CountryChina
- Language:Chinese
-
Abstract:
Anastomotic leakage is a serious complication in colorectal surgery;The healing of intestine is still the hot spot of current research.Methods of estimating intestinal healing mainly include mechanical,biochemical,immunohistochemical and hitological Method.The estimating parameters mainly Comprise bursting pressure,breaking strength,the amount of collangen and matrix metalloproteinase(MMP),and the scale for histology.The measurement of collagen and MMP is the nost import ant index for estimating healing of intestinal anastomoses.Collagen is the most abundant extracellular matrix protein that determines the mechanical stability of the connective tissue during wound healing.Collagen degradation is usually the result of the synergistic action of several MMPs.
