A control study on the curative effect and reliability of escitalopram with paroxetine for treatment of depression
- VernacularTitle:国产依地普仑与帕罗西汀治疗抑郁症临床疗效和安全性的对照研究
- Author:
Li WANG
;
Maosheng FANG
;
Wei ZHONG
- Publication Type:Journal Article
- Keywords:
Escitalopram;
Paroxetine;
Depression
- From:Chinese Journal of Behavioral Medicine and Brain Science
2008;17(3):225-226
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate efficacy and safety of escitalopram in treating depression. Methods In this randomized, double-blind, double-mimicry, paroxetine parallel controlled study,the study group was treated with escitalopram and the control group with paroxetine. Hamilton Rating Scale for Depression was taken to evaluate efficacy score. Results At the end of six weeks,compared with the total scores of HAMD before and after treatment, escitalopram (17.5±7.8) and paroxetine (16.0±7.9) group both showed the significant difference, while the difference compared between two groups ,the efficacy (87.0% and 81.7%) for depression and side effects were no significance. Conclusion Escitalopram is an efficient and safety antidepressant.
