The clinical observation to the consociation treatment that losartan potassium combined with enalapril used in treating Ⅳ phase diabetic nephropathy
- VernacularTitle:氯沙坦钾和依那普利联合治疗Ⅳ期糖尿病肾病的临床观察
- Author:
Xiaotao JIA
;
Kun LI
;
Xirong YANG
;
Xianying LU
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathy;
Losartan potassium;
Enalapril
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(9):16-18
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the curative effect that losartan potassium combined with enalapril used in treating Ⅳ phase diabetic nephropathy(DN). Methods Divided 74 Ⅳ phase DN suffers into 3 groups randomly.Losartan group:taken losartan potassium lablets 100 mg once every day orally,enalapril group:taken enalapril tablets 10 mg once every day orally,consociation group:taken the two drugs above ai one time with the same dosage.The treatment in the 3 groups were all above 3 years.monitoring the 24-hour albuminuria and SCr back and forth the treatment.Results It worthed statistics meaning that the 24-hour albuminuria in the 3 groups all declined(P＜0.05).The effect of consociation group did better(P＜O.01).In term of SCr,it declined in the consociation group worthed statisties meaning only.Conclusion The consociation application with losartan potassium and enalapril can control the proteinuria of Ⅳ phage DN suffers efficiently as well as defer process of kidney diseases.
