Transcatheter thrombolysis via the small saphenous vein for acute lower limb deep venous thrombosis
- VernacularTitle:经小隐静脉插管导管溶栓治疗下肢深静脉血栓形成
- Author:
Xiaozhong HUANG
;
Wei LIANG
;
Jiwei ZHANG
- Publication Type:Journal Article
- Keywords:
Venous thrombosis;
Urinary plasminogen activator;
Catheter ablation;
Small saphenous vein
- From:
Chinese Journal of General Surgery
2008;23(3):183-185
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate transcatheter thrombolysis via the small saphenous vein in the treatment for lower limb acute mix-deep venous thrombosis. Method From Jan 2005 to Mar 2007.37 patients with lower limb acute mix-DVT underwent catheter-directed thrombolysis via the small saphenous vein with urokinase(149 ±71)×104 IU continuous infusion.The venous patency score and the rate of patency improvement were observed by venograms before and after therapy.Twenty-two patients were followed up for(12 ±4)months. Results Venous patency score were significantly improved(Z=-5.330,P<0.01).The mean rate of venous patency was 50.17%±15%,and there was no complication.Venogram on 6~12 month follow up showed a venous patency of 58%±13%(Z=-3.545,P<0.01),and that on 13~18 months was 68%±20%(Z=-2.201,P<0.05). Conclusion This preliminary experience suggests that catheter-directed thrombolysis via the small saphenous vein with urokinase for acute lower limb mix-DVT iS safe and effective.