Which patients are likely to have a persistent hypersplenism after liver transplantation for the treatment of dysfunctional liver cirrhosis and hypersplenism
- VernacularTitle:脾功能亢进患者肝移植术后脾功能恢复不良的原因分析
- Author:
Fengxue ZHU
;
Jie Lü
;
Jiye ZHU
;
Guangming LI
;
Lei HUANG
;
Dong WANG
;
Xisheng LENG
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Hypersplenism;
Splenomegaly;
Hypertension,portal
- From:
Chinese Journal of General Surgery
2008;23(3):206-208
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the recovery of normal splenic function of hyperplenism in patients of liver transplantation. Methods In this study,93 liver transplant patients(all with pretransplant hypersplenism)were divided into group in which the platelet count become normal and the group in which the platelet count failed to recover. Results Hypersplenism disappeared after transplantation in 60 patients(64.5%),hypersplenism after transplantation persisted in 33 patients (35.5%);the portal vein pressure in new liver period,the splenic veinous blood flow after transplantation and the size of spleen were all significantly different between the two groups.The platelet count on three months after operation significantly correlates with pretransplant platelet count,the size of the spleen,the portal vein pressure in new liver phase and the posttransplant size of spleen.Conclusions The persistence of hypersplenism after liver transplantation is common,in may correlate with an unsatisfactory fall in portal pressure after transplantation,characteristics of splenomegaly and poor splenic venous blood flow.
