Lentiviral vectors in cancer immunotherapy
- VernacularTitle:慢病毒载体在肿瘤免疫治疗中的应用
- Author:
Shan LIN
;
Bing WANG
;
Lie WANG
- Publication Type:Journal Article
- Keywords:
lentivirus;
vector;
vaccine;
cancer;
immunotherapy
- From:
International Journal of Surgery
2008;35(3):168-171
- CountryChina
- Language:Chinese
-
Abstract:
Lentiviral vectors can transduce a wide range of different cell types.It can transduce not only dividing cells but also nondividing cells.It can be the immunotherapy tool for cancer therapy.Lentiviral yeators have several advantages,amongst which long-term expression,low toxicity,high capacity and low antivector immunity,they will play an important role and will attract more and more interest as an immunotherapeutic.Here,we discussed the clinical application and safety of the lentiviruses encoding tumor-associated antigen(TAA).
