Comparison of propofol-remifentail and propofol-fentanyl anesthesia for painless artificial abortion
- VernacularTitle:丙泊酚复合瑞芬太尼或芬太尼麻醉用于无痛人工流产临床观察
- Author:
Dongmei SU
;
Riu LIU
;
Bo SUI
;
Wei ZHANG
- Publication Type:Journal Article
- Keywords:
Abortion,induced;
General anesthesia;
Remifentanil;
Fentanyl;
Anesthesia,goneral
- From:
Chinese Journal of Primary Medicine and Pharmacy
2008;15(2):249-250
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe and compare the efficacy and safety between propofol-remifentanil and propofol-fentanyl for anesthesia of artificial abortion.Methods 200 ASA I patients scheduled for painless artificial abortion were randomly divided into two groups.R group were given intravenous remifentanil 1.0μg/kg then propofol 1～1.5mg/kg(n=100);F group were given intravenous fentanyl 0.05mg then propofol 1～1.5mg/kg(n=100).Total propofol dosage,analgesic effect during intro-and post-operative,consciousness loss time,wake-up time and independenly leaving time were recorded.BP,HR,SpO2 and side effects such as nausea and vomiting were observed during intro-and post-operative.Results The dosage of propofol was less in group R than that in group F[(80.4±10.8)mg vs(110.1±13.6)mg,P＜0.01)];consciousness loss time,wake-up time and independenly leave hospital time were shorter in group R than that in group F(P＜0.05);SpO2 down range and rate were significandy higher in group R(P＜0.05);Incidence of nausea and somnolence in group R was obviously lesS than that in group F.Conclusion Artifical abortion can be preformed effectively and safely with propofol-remifentanil or propofol-fentanyl,but propofol-remifentanil especially fits for painless artificial abortion compared with propofol-fantanyl.
