Relative study of serum C-reactive protein level in patients with acute massive cerebral infarction with multiple organ dysfunction syndrome
- VernacularTitle:急性大面积脑梗死并发多器官功能障碍综合征患者血清C-反应蛋白水平相关性研究
- Author:
Yanfang YANG
;
Lijun REN
;
De ZHANG
;
Chunhong LIU
;
Zibin ZHANG
;
Qiang HAO
;
Lihai CUI
- Publication Type:Journal Article
- Keywords:
C-reactive protein;
Brain infarction;
Multiple organ failure
- From:
Chinese Journal of Postgraduates of Medicine
2008;31(10):26-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the serum C-reactive protein (CRP) level in patients with acute cerebral infarction and acute massive cerebral infarction with multiple organ dysfunction syndrome (MODS),and analyze the clinical value of CRP. Methods The serum CRP level of 50 patients of control group and 50 patients of cerebral infarction admitted to hospital within 7 days (30 patients were admitted into acute cerebral infarction group and 20 patients into acute massive cerebral infarction with MODS group) were determined by immune scatter turbidimetry. Results (1)In cerebral infarction patients,serum CRP level in 48 cases(96%) was equal and over 5 mg/L.In control group,serum CRP level in 3 cases(6%) was equal and over 5 mg/L(P＜0.0 5).(2)The level of serum CRP acute in cerebral infarction group and in acute massive cerebral infarction with MODS group increased significantly than that in control group (P＜0.01).The level of serum CRP in acute massive cerebral infarction with MODS group increased significantly than that in acute cerebral infarction group.(3)When the level of CRP＜25 mg/L,the incidence of MODS in patients with acute cerebral infarction was zero.When the level of CRP≥25 mg/L,the incidence of MODS increased gradually with the rise of CRP. Conclusions There is positive correlation between the serum level of CRP and the severity of acute cerebral infarction and the incidence of MODS.CRP is a useful marker in predicting the prognosis of acute massive cerebral infarction with MODS.
