Expression of c-erbB-2in breast cancer
- VernacularTitle:乳腺癌细胞中c-erbB-2表达的临床意义
- Author:
Ming CHEN
;
Xiaolong QI
;
Renzhi WEI
- Publication Type:Journal Article
- Keywords:
Breast cancer;
c-erbB-2
- From:
Clinical Medicine of China
2007;23(13):51-52
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of c-erbB-2 in breast cancer and its relationship with prognosis.Methods The expression of c-erbB-2 in breast cancer was detected by immunohistochemistry assays in 60 cases of breast cancer.Results The positive expression level of c-erbB-2 in invasive breast cancer was signifi-cantly higher than that in other kinds of breast cancer(P<0.01).The positive expression level of c-erbB-2 in the metastatic breast cancer with four lymph nodes was higher than in the early cancer with no lymph node involvement (P<0.01).The 10 years survival rate in negative expression of c-erbB-2 was higher than in positive expression(P<0.05).Conclusion c-erbB-2 is important for physicians to instruct the treatment of the breast cancer and judge the prognosis.
