The study on pain evoked potentials in patients with amyotrophic lateral sclerosis
- VernacularTitle:痛觉诱发电位示肌萎缩侧索硬化患者痛觉通路正常
- Author:
Jun ZHANG
;
Yingsheng XU
;
Juyang ZHENG
;
Shuo ZHANG
;
Dexuan KANG
;
Dongsheng FAN
- Publication Type:Journal Article
- Keywords:
Amyotrophic lateral sclerosis;
Evoked potentials,somatosensory;
Nociceptors
- From:
Chinese Journal of Neurology
2008;41(1):5-7
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the features of pain evoked potentials in patients with amyotrophic lateral sclemsis(ALS)and evaluate the pain pathway in these patients.Methods Sixty patients with ALS and 60 controls were set on supine position.The contact heat evoked potential stimulator with a diameter of 27 mm and an area of 573 mm2was used to elicit pain and contact heat evoked potentials(CHEP)in an accelerating speed of 70 ℃/s.Thermal stimuli were given at 54.5 ℃ to three body sites:the dorsum of hand,proximal volar for aml and C7. CHEP was recorded at spots of Cz and Pz.The features of CHEP was observed At the same time,somatosensory evoked potential(SEP)was assesed.Results The figure and latency of CHEP in ALS patients were normal.The latency was:the dorsum of hand:(561.2±28.6)ms; proximal volar forarm:(540.1±39.2)ms;C7:(512.7±31.4)ms.There were no significant differences of latency and SEP between tlle ALS patients and the controls((558.7±30.2),(536.6±23.5), (501.8±26.0)ms,t=4.23,4.51,3.74,P＞0.05).Conclusion Patients with ALS have a normal CHEP,suggesting that the pain pathway in patient with ALS is intact.
