The causes of death for 89 HIV/AIDS patients
- VernacularTitle:89例HIV/AIDS患者死亡原因分析
- Author:
Yufang ZHENG
;
Xueyan JIANG
;
Tangkai QI
;
Li LIU
;
Renfang ZHANG
;
Yinzhong SHEN
;
Jiangrong WANG
;
Hongzhou LU
- Publication Type:Journal Article
- Keywords:
HIV-1;
Acquired immunodeficiency syndrome;
Cause of death;
CD4+ T lymphocyte count;
Infection
- From:
Chinese Journal of Clinical Infectious Diseases
2008;1(1):27-29
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the causes of death for 89 HIV/AIDS patients,and the association of CD4+ T lymphocyte counts with the mortality.Methods Data were collected from 89 deceasedpatients who were admitted to Shanghai Public Health Clinical Center from Jan 1996 to Sep 2007,and wereretrospectively analyzed with t-test.Results Heterosexual,blood transfusion and blood products were themajor transmission routs for 89 deceased HIV/AIDS patients.The primary causes of death varied with different levels of CD4+ T lymphocyte counts.With higher CD4+T lymphocyte counts,patients were more likelyto die from non-AIDS-related opportunistic infections such as upper digestive tract hemorrhage.Serious pulmonary infection induced by various etiologies was the primary cause of death.Co-infections of multiple etiologics were often seen in these death cases.Conclusion Opportunistic infection is the primary cause of death for HIV/AIDS patients.Appropriate therapies should be based on CD4+ T lymphocyte counts and patients' specific conditions to reduce the mortality.