Naloxone and acute organophosphorus pesticide poisoning-related respiratory failure
- VernacularTitle:纳洛酮促进急性有机磷农药中毒呼吸衰竭恢复的临床观察
- Author:
Jiaguo WU
- Publication Type:Journal Article
- Keywords:
Poisoning;
Naloxone
- From:
Chinese Journal of General Practitioners
2008;7(1):53-54
- CountryChina
- Language:Chinese
-
Abstract:
This study was to examine the influence of Naloxone on respiratory failure among patients with acute organophosphorus pesticide poisoning(AOPP). From June 1997 to May 2000, 106 AOPP-related respiratory failure patients were assigned to the control group. During June 2000 to September 2002, 83matched patients were assigned to the treatment group and obtained intravenous Naloxone injection. Duration of mechanical ventilation was recorded. In comparison to the treatment group, the control group showed prolonged mechanical ventilation[(342±123)h vs(235±89)h;t=6. 92, P＜0. 01], demonstrating that intravenous Naloxone injection may promote the reoccurrence of independence-breathing in AOPP-related respiratory failure patients.
