Combination of western and Chinese traditional medicine in treatment of chronic obstructive pulmonary disease with acute exacerbation
- VernacularTitle:中西药物结合治疗慢性阻塞性肺疾病急性加重期患者
- Author:
Guang LI
- Publication Type:Journal Article
- Keywords:
Lung disease,obstructive;
Anticoagulants(TCD)
- From:
Chinese Journal of General Practitioners
2008;7(1):62-63
- CountryChina
- Language:Chinese
-
Abstract:
Eighty patients with acute exacerbation of chronic obstructive pulmonary disease(COPD)complicated by pulmonary artery hypertention(PAH)were recruited in the study. All patients took conventional western medicine, among them 40 also received injection of Chinese herb medicine Shenxiong(study group)for 14 days. Mean pulmonary artery pressure(mPAP), plasma platelet alphagranule membrane protein(GMP-140), thromboxane B2(TXB2)and 6-keto-prostaglandin F1α(6-K-PGF1α)were measured before and after treatment in both groups. Compared with pretreatment levels and levels in control group mPAP, GMP-140 and TXB2 levels in study group were significantly decreased, while the levels of 6-K-PGF1α were significantly increased. The results indicate that Shenxiong injection may inhibit platelet activation and reduce mPAP.
