Effects of Naloxone and Methylprednisolone on therapy of severe bronchiolitis
- VernacularTitle:纳洛酮联合甲泼尼龙佐治难治性毛细支气管炎疗效观察
- Author:
Yanbo LIU
;
Yunpeng HAO
;
Shufang HUO
- Publication Type:Journal Article
- Keywords:
Bronchiolitis;
Naloxone;
β-endorphin;
Methylprednisolone
- From:
Chinese Pediatric Emergency Medicine
2007;14(z1):15-16
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effects of Naloxone and Methylprednisolone(MPS) on therapy of severe bronchiolitis. Methods 98 cases of severe bronchihtis were randomly divided into 2 groups,the Naloxone/MPS treating group and the control group,the later only give regular treatment. Results The Naloxone/MPS treating group scored significantly lower at the time of 48 hours and 5 days(P<0.001),according to cough,dyspnia and other respiratory symptoms,and the efficacy of Naloxone/MPS treatment is appreciately higher than control(P<0.01). Conclusion Naloxone and MPS therapy shows remarkable clinical beneficial effects on severe bronchiolitis.