Differential Diagnosis of Breast Mass and Staging of Breast Cancer Using F-18-FDG PET.
- Author:
Jeong Seok YEO
;
Dong Soo LEE
;
Keon Wook KANG
;
Dong Young NOH
;
June Key CHUNG
;
Myung Chul LEE
- Publication Type:Original Article
- Keywords:
Breast cancer;
F-18 FDG PET
- MeSH:
Breast Neoplasms*;
Breast*;
Diagnosis, Differential*;
Female;
Humans;
Inflammation;
Lymph Nodes;
Neoplasm Metastasis;
Positron-Emission Tomography;
Sensitivity and Specificity
- From:Korean Journal of Nuclear Medicine
1999;33(6):502-511
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: F-18-fluorodeoxyglucose (FDG) positron emission tomography (PET) has been proven to be useful in the differential diagnosis of breast mass and staging of breast cancer. This study assessed the diagnostic accuracy of F-18-FDG PET in the differentiation of breast mass and staging of breast cancer. MATERIALS AND METHODS: Total 42 patients who had breast mass underwent F-18-FDG PET (all female, 40+/-10 year old). We compared F-18 FDG PET results with pathologic findings in 24 patients RESULTS: In the differentiation of breast mass, sensitivity and specificity were 95% (19/20) and 77% (7/9) respectively. Three false positive cases were due to inflammation and one false negative patient had small tumor less than 1 cm. In the assessment of axillary lymph node status, sensitivity and specificity were 73% (8/11) and 100% (7/7) respectively. We found distant metastasis that were not suspected before F-18-FDG PET in 2 patients. CONCLUSION: F-18-FDG PET shows good diagnostic performance in differentiation of breast mass and staging of breast cancer.
