Intensive insulin therapy: its effect on the prognosis of critically ill patients
- VernacularTitle:强化胰岛素血糖控制治疗对危重症患者预后的影响
- Author:
Jiayan NAN
;
Benzhang ZHU
;
Ye GAO
;
Yan HAN
;
Qiyun ZHANG
- Publication Type:Journal Article
- Keywords:
Insulin;
Anti-inflammatory effects;
NF-κB;
Intercellular adhesion molecule-1
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(2):141-142
- CountryChina
- Language:Chinese
-
Abstract:
A total of 62 critically ill patients were randomly allocated to the intensive insulin therapy group and the conventional insulin therapy group. The effect of therapy on the prognosis, the activity of NF-κB in peripheral blood monouclear cells and plasma intercellular adhesion molecule-1 level were investigated. The results showed that the intensive insulin therapy may improve the prognosis and insulin had a reliable anti-inflammatory effect in the critically ill patients.