Clinical safety of preoperative lymphatic chemotherapy in the treatment of rectal cancer
- VernacularTitle:直肠癌术前淋巴化疗安全性分析
- Author:
Qiang MENG
;
Ronggui MENG
;
Long CUI
;
Guanglie LING
;
Bing LIU
- Publication Type:Journal Article
- Keywords:
Rectal cancer;
Lymphatic chemotherapy
- From:
Chinese Journal of Digestive Surgery
2008;7(2):137-139
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical safety of preoperative lymphatic chemotherapy in the treatment of reetal cancer.Methods The regional and systemic symptoms,postoperatwe stoma healing,haematogenesis.functions of hean,liver and kidney after lymphatic chemotherapy,and the level of CD3+,CD4+,CD8+,CD4+/CD8+,CD(16+56)+in blood 30 minutes before and 48 hours after lymphatic chemotherapv were detected.Results There were no significant effects of lymphatic chemotherapy on the regional and systemic symptoms,postoperative stoma healing,haematogenesis and the functions of heart,liver and kidney.The level of CD4+/CD8+48 hours after lymphatic chemotherapy was significantly increased(t=7.145,P＜0.05),while no significant changes of CD3+,CIM+,CD8+,CD(16+56)+were detected(t=1.782,1.151,1.184,0.955,P＞0.05),when compared with those 30 minutes before lymphatic chemotherapy.Conclusions Preoperative lymphatic chemotherapy is safe and can enhance patients'immunity in early stage.
