Glycemic excursion-induced islet-like cells in rat bone marrow
- VernacularTitle:血糖波动诱导大鼠骨髓出现胰岛样细胞
- Author:
Xiaohong WU
;
Jian ZHU
;
Jingjing JIANG
;
Yu XU
;
Cuiping LIU
;
Xiaodong MAO
;
Kuanfeng XU
;
Chao LIU
- Publication Type:Journal Article
- Keywords:
Glucose excursion;
Bone marrow;
Islet-like cells;
Rats;
Sprague-Dawley
- From:
Chinese Journal of Endocrinology and Metabolism
2008;24(2):208-209
- CountryChina
- Language:Chinese
-
Abstract:
Glycemic excursion was induced in SD rats by intraperitoneal injection of 50% glucose solution, and cells isolated from bone marrow of these rats showed cell clusters which expressed insulin, c-peptide, glucagon, somatostatin and islet amyloid polypeptide, and other genes related to islet-cells development and functions.
