A Case of Zollinger-Ellison Syndrome with Gastrinoma Localized by 111In-Pentetreotide Scan.
- Author:
Hyeon Jo JEONG
;
Jin Sook RYU
;
Jae Seung KIM
;
Dae Hyuk MOON
;
Hwoon Yong JUNG
;
Hyun Kwon HA
;
Hee Kyung LEE
- Publication Type:Case Report
- Keywords:
Somatostatin receptor scintigraphy;
Gastrinoma;
Zollinger-Ellison syndrome
- MeSH:
Binding Sites;
Gastrinoma*;
Humans;
Korea;
Neuroendocrine Tumors;
Radionuclide Imaging;
Receptors, Somatostatin;
Somatostatin;
Zollinger-Ellison Syndrome*
- From:Korean Journal of Nuclear Medicine
1999;33(6):537-542
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In patient with Zollinger-Ellison syndrome, it is difficult to localize gastrinoma because the tumor is frequently small and multiple. However, accurate localization of the tumor is important for the treatment. Among various imaging modalities, somatostatin receptor scintigraphy (SRS) has been recognized to be the most sensitive tool for the detection of neuroendocrine tumors such as gastrinomas based on the presence of high-affinity binding sites for somatostatin. Recently, we experienced a case of Zollinger-Ellison syndrome caused by gastrinomas which was localized by SRS. This is the first case report of gastrinoma detected by SRS in Korea. SRS can facilitate tumor detection in patient with Zollinger-Ellison syndrome and should be considered as the first-line diagnostic method in the early course of the disease.
