X-ray and high resolution CT Findings in pulmonary alveolar proteinosis and their relationship with pulmonary function
- VernacularTitle:肺泡蛋白沉着症X线胸片及高分辨率CT表现与肺功能的关系
- Author:
Lu ZHOU
;
Zhuhua ZHANG
;
Zhengyu JIN
- Publication Type:Journal Article
- Keywords:
Pulmonary alveolar proteinosis;
Respiratory function tests;
Radiography;
thoracic;
Tomograghy;
X-ray computed
- From:
Chinese Journal of Radiology
2008;42(2):145-148
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study X-ray and high resolution computed tomograghy(HRCT)features and tIleir relationship with pulmonary function test in pulmonary alveolar proteinosis(PAP).MethodsThe findings of X-ray and HRCT and the Resultsof pulmonary function tests in 19 patients with PAP were reviewed retrospectively.X-ray and HRCT scores were rated in the aspects of opacity density,extent,and severity.The relationship between the imaging scores and pulmonary function tests were determined.ResultsX-ray showed a symmetrical perihilar predominance appearance in patients with PAP.HRCT scan showed bilateral clear-defined pathchy areas of ground-glass opacity and interlobular septal thickening,a pattern commonly characterized as"crazy paving".Nineteen PAP respiratory function Resultswere:DLCO/Pred=(54.49±16.78)%,FEV1/FVC=(86.00±6.70)%.Chest radiographic extent score and severity score correlated with diffusing capacity(r=-0.661,P＜0.01,r=-0.475,P＜0.05).HRCT severity score was 16.47±5.26.Among all the HRCT scores,severity score correlated significantly with the presence of restrictive ventilatory defect and diffusing capacity defect(DLCO/Pred,r=-0.809,P＜0.01;FEV1/FVC,r=0.573,P＜0.05).ConclusionsIn patients with PAP,there Is close relationship between X-ray,HRCT findings and pulmonary function.HRCT correlates more closely with pulmonary function.
